Medicine

Advancing ASO treatments from development to execution

.Completing enthusiasms.R.S., M.S., H.G. and also A.A.R. are planners of the 1M1M project. H.G. and also A.A.R. are actually panel of directors participants and also R.S., M.S. as well as A.A.R. are actually participants of the clinical consultatory committee of N1C. A.A.R. makes known employment by LUMC, which possesses licenses on exon-skipping modern technology, some of which has been actually accredited to BioMarin and also consequently sublicensed to Sarepta. As co-inventor of a few of these patents, A.A.R. was actually allowed to a share of royalties. A.A.R. additionally makes known acting as ad hoc professional for PTC Therapies, Sarepta Therapies, Regenxbio, Dyne Rehabs, Lilly, BioMarin Pharmaceuticals Inc., Eisai, Entrada, Takeda, Splicesense, Galapagos, Sapreme, Italfarmaco and also Astra Zeneca. Over the last 5 years, A.A.R. also executed impromptu seeking advice from for Alpha Anomeric. A.A.R. likewise reports registration of the medical advisory boards of Eisai, Hybridize Therapeutics, Muteness Therapies, Sarepta Therapies, Sapreme and Mitorx. Over the last 5 years, A.A.R. was actually likewise a medical board of advisers member for ProQR. Pay for A.A.R. u00e2 s consulting and advising activities is actually paid to LUMC. In the past 5 years, LUMC likewise acquired sound speaker gratuity from PTC Rehabs, Alnylam Netherlands, Italfarmaco and Pfizer and cashing for arrangement research study coming from Sapreme, Eisai, Galapagos, Synaffix and also Alpha Anomeric. Project funding is acquired from Sarepta Rehabs and also Entrada by means of unrestricted gives. H.G. has absolutely nothing to make known in connection with the subject matters dealt with in this document. Before 5 years, he has actually additionally received consultancy honoraria from UCB. M.S. got consultancy gratuity coming from Ionis, UCB, Prevail, Orphazyme, Biogen, Servier, Reata, GenOrph, AviadoBio, Biohaven, Zevra, Lilly and also Solaxa before 5 years, all unrelated to the here and now composition. R.S. possesses nothing to divulge in relation to the subject matters dealt with in this particular composition. She has actually obtained audio speaker and/or working as a consultant gratuity or even financing contributions from Abbvie, Bial, STADA and also Everpharma previously 5 years.